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Updated: May 12, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
[Association between age and chorioretinal hemodynamics in normal volunteers examined with laser speckle flowgraphy]
Akiko Tamura1, Akiko Kogure, Goro Watanabe
1Department of Opthalmology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. a-tamura@oph.twmu.ac.jp
Purpose:
To investigate the relationship between age and chorioretinal hemodynamics in normal volunteers examined with Laser speckle flowgraphy (LSFG-NAVI).
Subjects And Methods:
107 eyes of 107 healthy volunteers aged from 21 to 78 years old were included. Laser speckle flowgraphy measurements of relative blood velocity (mean blur rate: MBR), skewness in the wave of blood velocity (Skew) and blowout score (BOS), which indicates ease of blood flow, were obtained as parameters of chorioretinal hemodynamics. MBR and BOS were measured on the optic disc and macula, and BOS and Skew were measured in retinal arteries and veins.
Results:
There was a negative correlation between age and MBR on the optic disc and macula. There was a negative correlation between age and BOS on the optic disc, macula, retinal arteries and retinal veins.
Conclusion:
There was a negative correlation between MBR, BOS and age in all measurement areas. MBR and BOS may serve as indexes for a new interpretation of fundus pathology including age-related arterial sclerosis.
