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Updated: May 12, 2026
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
[Value of computed tomography features for prognosis evaluation of gastrointestinal stromal tumor]
Zhen-peng Peng1, Can-hui Sun, Yan-ji Luo
1Radiology Department, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Objective:
To analyze the association between CT features and survival rate of GIST, and to elucidate the significance of CT features for prognosis.
Methods:
Clinical data of 38 patients with pathologically and immunohistochemically proven GISTs, including 11 patients at high biological risk, 13 at moderate risk, 10 at low risk and 4 at very low risk. Patients who underwent CT examination for primary tumors were included. Association between CT features and survival rate was examined.
Results:
The mean follow-up period of 38 cases was 42.6 months and the 3-year survival rate was 86.8%. Univariate analysis revealed that tumor growth pattern, diameter, lobulated shape, irregular margin, necrosis, ulceration, adjacent invasion, and liver metastasis were associated factors of 3-year survival rate. Circumference invasion and hepatic metastases predicted poor 3-year survival rate (P<0.05). Calcification and intensity were not associated with prognosis (P>0.05).
Conclusions:
CT can demonstrate the tumor growth pattern, size, shape, boundary, density, necrosis, hemorrhage, calcification, ulcer, enhance features and metastasis. CT can play an important role in estimating the survival rate of GIST.
