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Updated: May 12, 2026

Nerve Excitability Assessment in Chemotherapy-induced Neurotoxicity
Published on: April 26, 2012
Chemotherapy-induced peripheral neuropathy: an algorithm to guide nursing management
Cindy Tofthagen1, Constance M Visovsky, Rachelle Hopgood
1College of Nursing, University of South Florida, Tampa, USA. ctofthag@health.usf.edu
Oncology nurses can now better manage chemotherapy-induced peripheral neuropathy (CIPN) with a new, practical algorithm. This tool aids in assessing physical function, managing symptoms, and improving patient safety and mobility.
Area of Science:
- Oncology Nursing
- Neurology
- Clinical Assessment
Background:
- Chemotherapy-induced peripheral neuropathy (CIPN) significantly impacts patients' quality of life.
- Assessing physical function is crucial for CIPN management but often overlooked.
- Complex neuromuscular symptoms present challenges in CIPN evaluation and care.
Purpose of the Study:
- To develop a feasible algorithm for oncology nurses to assess and manage CIPN.
- To provide practical guidance for implementing CIPN assessment in diverse clinical settings.
- To standardize nursing care for patients experiencing CIPN.
Main Methods:
- Development of a clinical algorithm for CIPN assessment and management.
- Focus on techniques easily implementable in various healthcare environments.
- Integration of baseline and ongoing physical function evaluations.
Main Results:
- A structured approach to CIPN assessment and management is proposed.
- The algorithm facilitates consistent and effective nursing interventions.
- Emphasis on practical application in routine oncology care.
Conclusions:
- The devised algorithm empowers oncology nurses to effectively manage CIPN.
- Prioritizing pain management, safety, and physical function is key.
- This tool addresses the need for standardized, accessible CIPN care strategies.
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