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The association between vitamin D status and recurrent wheezing

Eda Özaydın1, Mehmet Fatih Bütün, Bahar Cuhacı Cakır

  • 1Infancy Service, Ankara Children's Health and Diseases Hematology-Oncology Education and Research Hospital, Ankara, Turkey, eozaydin2001@yahoo.com.

Indian Journal of Pediatrics
|March 30, 2013
PubMed

Insights

This study found no significant link between vitamin D levels and recurrent wheezing in infants. While many infants had low vitamin D, it did not appear to cause or worsen wheezing symptoms.

Area of Science:

  • Pediatrics
  • Nutritional Science
  • Respiratory Medicine

Background:

  • Recurrent wheezing is a common issue in infants, impacting their respiratory health.
  • Vitamin D plays a crucial role in immune function and has been explored for its potential effects on respiratory illnesses.

Purpose of the Study:

  • To determine if there is an association between vitamin D status and the occurrence of recurrent wheezing in infants.
  • To compare serum 25-hydroxyvitamin D [25(OH)D] levels in infants with and without recurrent wheezing.

Main Methods:

  • A case-control study involving 30 infants with recurrent wheezing and 45 healthy controls.
  • Serum 25-hydroxyvitamin D [25(OH)D] levels were measured, and clinical features were recorded.
  • Statistical analysis was conducted using SPSS software.

Main Results:

  • Mean 25(OH)D levels were 18.8 ± 11 IU/L in the wheezing group and 22.1 ± 8.9 IU/L in the control group.
  • A high prevalence of vitamin D deficiency (<20 ng/ml) and insufficiency (<30 ng/ml) was observed in both groups.
  • No statistically significant difference in 25(OH)D levels was found between infants with recurrent wheezing and controls.

Conclusions:

  • The study did not find a significant association between vitamin D status and recurrent wheezing in infants.
  • Despite high rates of vitamin D deficiency, it was not linked to recurrent wheezing in this cohort.
  • Further research may be needed to explore other factors influencing infant wheezing.
Abstract

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