Related Experiment Video
Updated: May 12, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Sinonasal papilloma in Chiang Mai University Hospital
Supranee Fooanant1, Thienchai Pattarasakulchai, Rak Tananuvat
1Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Objective:
To study sinonasal papilloma patients in terms of clinical characteristics, treatment, outcome, and complications.
Material And Method:
A retrospective descriptive study was done. Sinonasalpapilloma data were gathered between 1999 and 2009. There were 63 available patients from the 82 cases.
Results:
There were nine cases of nasal papilloma (14.3%) and 54 of inverted papilloma (85.7%). The mean age of the inverted papilloma group was higher than the nasal papilloma group (54 +/- 12.97 years vs. 42.4 +/- 24.8 years). The most common symptom was unilateral nasal obstruction. There were three cases of synchronous malignancy in the inverted papilloma and two metachronous (9.3%). Thirty-nine patients (72%) could be followed-up for more than three months. Recurrence was more common in the inverted papilloma group than nasal papilloma (37% vs. 11.1%). The 50% recurrent time of the endoscopic group was 51 weeks and the external group was 14 weeks. The recurrence of the external approach group was 1.59 times the endoscopic group. Ten surgical complications were found in eight inverted papilloma patients (16%) and included three in the endoscopic and five in the external group. Most of them were minor They were hypoesthesia and epiphora.
Conclusion:
Sinonasal inverted papilloma was common, able to recur and associated with malignancy. Though this was a limited retrospective study, it showed lower recurrence on the endoscopic approach. The life-long follow-up is needed in all cases.
Insights
Sinonasal inverted papilloma is common and can recur, sometimes with malignancy. Endoscopic surgery shows lower recurrence rates than external approaches, necessitating lifelong follow-up for patients.
Area of Science:
- Otolaryngology
- Pathology
Background:
- Sinonasal papillomas are benign tumors with varying clinical behaviors.
- Inverted papilloma is the most common subtype, often associated with recurrence and malignant transformation.
Purpose of the Study:
- To analyze the clinical characteristics, treatment outcomes, and complications of sinonasal papilloma patients.
- To compare recurrence rates and complications between different surgical approaches.
Main Methods:
- Retrospective descriptive study of 82 sinonasal papilloma cases from 1999-2009.
- Analysis of 63 available patient records, categorizing by papilloma type (nasal vs. inverted).
- Comparison of recurrence rates and complications based on surgical approach (endoscopic vs. external).
Main Results:
- Inverted papilloma (85.7%) was more common than nasal papilloma (14.3%).
- Unilateral nasal obstruction was the most frequent symptom.
- Inverted papilloma showed higher recurrence rates (37%) and a higher association with malignancy (9.3%) compared to nasal papilloma.
- Endoscopic surgery demonstrated lower recurrence rates (51 weeks 50% recurrent time) than the external approach (14 weeks 50% recurrent time).
- Surgical complications occurred in 16% of inverted papilloma patients, with minor issues like hypoesthesia and epiphora being most common.
Conclusions:
- Sinonasal inverted papilloma is a prevalent condition with significant recurrence potential and association with malignancy.
- The endoscopic surgical approach appears to offer lower recurrence rates compared to the external approach.
- Lifelong follow-up is crucial for all sinonasal papilloma patients due to the risk of recurrence and malignant transformation.
