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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Multiphase computed tomography of malignant kidney tumors: radiologic-pathologic comparison
Ivan Zokalj1, Miljenko Marotti, Hussein Saghir
1Department of Radiology and Ultrasound, Cakovec County Hospital, Cakovec, Croatia. ivan.zokalj@ck.t-com.hr
Acta Clinica Croatica
|April 2, 2013
Summary
Multiphase spiral computed tomography (CT) effectively detects and characterizes malignant renal tumors. While accurate for most local extensions, CT shows limitations in identifying main renal vein invasion.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Malignant renal tumors require accurate diagnostic imaging for effective treatment planning.
- Computed tomography (CT) is a key modality in evaluating kidney cancers.
- Assessing the diagnostic performance of multiphase spiral CT is crucial.
Purpose of the Study:
- To evaluate the diagnostic test parameters of multiphase spiral CT for malignant renal tumors.
- To assess CT's accuracy in tumor detection, characterization, and local extension evaluation.
- To compare CT findings with histopathology for validation.
Main Methods:
- Retrospective review of 51 patient records.
- Utilized multiphase spiral CT with unenhanced and postcontrast scans (arterial and nephrographic phases).
- Compared CT findings against surgical pathology results.
Main Results:
- High sensitivity (96.08%) and accuracy for tumor detection and characterization.
- Excellent sensitivity for detecting tumor spread into the collecting system (100%).
- Variable performance in detecting fibrous capsule penetration (91.97% sensitivity) and lymph node involvement (75% sensitivity).
- Limited sensitivity (60%) but high specificity (100%) for main renal vein invasion.
- Strong correlation (0.916) between CT and pathology for tumor size.
Conclusions:
- Multiphase spiral CT demonstrates satisfactory diagnostic parameters for detecting and characterizing renal tumors.
- CT is effective in evaluating most aspects of local tumor extension.
- Identification of main renal vein invasion remains a limitation of this imaging technique.
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