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Updated: May 12, 2026

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Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish
Published on: April 22, 2017
In vitro maturation remains an interesting procedure.
1Department of Obstetrics and Gynecology, Hôpital FOCH de Suresnes, Suresnes, France. frydmanrene@gmail.com
Fertility and Sterility
|April 2, 2013
Summary
Live births from in vitro maturation (IVM) oocytes are rising. This review summarizes current data on the health outcomes of infants born following IVM procedures.
Area of Science:
- Reproductive Medicine
- In Vitro Maturation (IVM)
- Neonatal Health
Background:
- In vitro maturation (IVM) is an assisted reproductive technology.
- The number of live births resulting from IVM oocytes has significantly increased globally over the last 20 years.
- Growing utilization necessitates understanding infant health outcomes.
Purpose of the Study:
- To review and present current data on the health status of infants born following IVM procedures.
- To consolidate findings from various studies on IVM infant health.
- To provide an overview for clinicians and researchers.
Main Methods:
- This study is a Views and Reviews article.
- Data were compiled from existing literature and clinical reports.
- Analysis focused on reported health data of infants conceived via IVM.
Main Results:
- The number of live births from IVM oocytes has shown a consistent upward trend.
- The review compiles available health data for infants born from IVM oocytes.
- Specific health concerns or developmental trends are detailed within the review.
Conclusions:
- The increasing trend in IVM live births highlights its growing importance in fertility treatments.
- Continued monitoring and reporting of IVM infant health are crucial.
- This review serves as a reference for the current understanding of IVM-associated neonatal health.
Related Concept Videos
In Vitro Fertilization
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
In vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
