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Updated: May 12, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Magnetic resonance imaging after translabyrinthine complete excision of vestibular schwannomas
James R Tysome1, David A Moffat
1Department of Neuro-otology and Skull Base Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Abstract:
The objective of this study is to determine whether magnetic resonance imaging (MRI) at 2 years following complete vestibular schwannoma (VS) excision using a translabyrinthine approach is sufficient to detect recurrent tumor. The study is set in a tertiary referral skull base unit. A service evaluation of a prospective database identified patients who underwent complete translabyrinthine VS excision with prospectively recorded MRI results at 2 and 5 years following surgery. The main outcome measures were evidence of tumor recurrence on MRI at 2 and 5 years after surgery. Of 314 patients in the study, all patients where MRI was reported to show no recurrence at 2 years (97%) also had no signs of recurrence on MRI at 5 years. All eight patients with MRI suspicious of recurrence (linear enhancement of internal auditory canal [IAC]) at 2 years had no progression on MRI at 5 to 15 years. One patient had evidence of definite recurrence (nodular enhancement of IAC) at 2 years, who went on to have radiosurgery at 8 years. Where patients have MRI with no linear enhancement of the IAC at 2 years, no further imaging is required. Where linear enhancement is seen, no change in enhancement at 5 years is reassuring and no further imaging is required.
