SPY-Q analysis toolkit values potentially predict mastectomy flap necrosis
Martin I Newman1, Megan C Jack, Michel C Samson
1Department of Plastic Surgery, Cleveland Clinic Florida, Weston, FL 33331, USA. newmanm@ccf.org
Annals of Plastic Surgery
|April 2, 2013
Summary
Quantitative relative perfusion values from SPY-Q software may improve prediction of mastectomy flap necrosis. This objective data can enhance clinical judgment of flap viability in breast reconstruction.
Area of Science:
- Surgical Oncology
- Medical Imaging
- Plastic Surgery
Background:
- SPY Intraoperative Perfusion Assessment System aids in predicting mastectomy flap necrosis.
- Current SPY image analysis is subjective.
- SPY-Q postprocessing software offers objective quantification using fluorescence intensity.
Purpose of the Study:
- To determine the utility of objective, numerical data from SPY-Q software in predicting mastectomy flap necrosis.
- To evaluate the role of quantitative perfusion values in assessing flap viability.
Main Methods:
- Retrospective analysis of 20 SPY images from immediate breast reconstructions.
- Selection of 10 images from breasts with flap necrosis and 10 with adequate healing.
- Evaluation using SPY-Q postprocessing software for absolute and relative fluorescence intensity.
Main Results:
- Mean relative fluorescence was significantly lower in the necrosis group (25.2%) compared to the adequate healing group (43.3%) (P < 0.001).
- Mean absolute fluorescence showed a trend towards lower values in the necrosis group (18.5 vs. 25.0), but was not statistically significant (P = 0.07).
Conclusions:
- Quantitative relative perfusion values from SPY-Q software may objectively augment clinical judgment of flap viability.
- This objective and reproducible data can aid in predicting mastectomy flap necrosis.
- Further studies may validate the use of SPY-Q in clinical practice.
