Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Burn Injuries

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Peripheral Artery Disease IV: Nursing Management

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bacterial and host factors affecting acquisition of <i>Streptococcus pneumoniae</i> in a murine model.

Infection and immunity·2026

Same author

Surgical care of the incarcerated patient.

The journal of trauma and acute care surgery·2026

Same author

Bacterial and host factors affecting acquisition of <i>Streptococcus pneumoniae</i> in a murine model.

bioRxiv : the preprint server for biology·2026

Same author

Complex Wound Reconstruction in a Patient With Ehlers-Danlos Syndrome.

Plastic and reconstructive surgery. Global open·2025

Same author

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.

Frontiers in immunology·2025

Same author

Data-driven consideration of genetic disorders for global genomic newborn screening programs.

Genetics in medicine : official journal of the American College of Medical Genetics·2025

Search research articles

Related Experiment Video

Updated: May 12, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Lower extremity nerve decompression in burn patients.

Cindy Wu¹, Catherine T Calvert, Bruce A Cairns

¹Division of Plastic Surgery, University of North Carolina Health Care System, Chapel Hill, NC 27516-7195, USA.

Annals of Plastic Surgery

|April 2, 2013

Summary

Peripheral nerve decompression in the lower extremities effectively treats sensory and motor deficits after burn injuries. This procedure offers significant functional improvement, even when performed long after the initial burn.

Related Experiment Videos

Last Updated: May 12, 2026

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain

Published on: March 15, 2024

Area of Science:

Neurosurgery
Burn Reconstruction
Peripheral Nerve Surgery

Background:

Peripheral nerve compression is a common yet challenging complication following burn injuries.
While upper extremity nerve decompression is documented, data on lower extremity procedures are limited.

Observation:

A retrospective review of 107 burn patients undergoing 19 lower extremity nerve decompressions over 10 years.
Procedures targeted common peroneal, superficial peroneal, saphenous, and sural nerves, a mean of 23 months post-injury.
Preoperative symptoms included foot drop and abnormal sensation; 10 of 11 tested patients had abnormal electrodiagnostic findings.

Findings:

73.6% of decompressions showed definite sensorimotor improvement, with 10.5% showing mild improvement.
Common peroneal nerve decompression was most frequent (15 procedures).
Low complication rates were observed, including wound dehiscence and cellulitis.

Implications:

Lower extremity nerve decompression is a viable and effective treatment for persistent sensorimotor dysfunction after burns.
The procedure has low morbidity and high potential for functional recovery, even late after injury.
Consideration for this intervention is recommended for patients with foot drop, paresthesias, or dysesthesias post-burn.