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Updated: May 12, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Elderly patients and coronary heart disease on response to treadmill exercise test
Jian-ling Sun1, Guo-lan Gao, Ying Zhao
1Department of Cardiology, Aviation General Hospital, An Ding Men Wai Bei Yuan Road 3, Beijing, 100012, People's Republic of China, sunjianling2000@yahoo.com.cn.
Insights
Elderly patients over 75 with coronary heart disease (CHD) show reduced exercise tolerance and altered treadmill exercise test (TET) parameters. TET is highly valuable for diagnosing CHD in older adults.
Area of Science:
- Cardiology
- Geriatrics
- Exercise Physiology
Background:
- Coronary heart disease (CHD) poses significant health challenges in the elderly population.
- Understanding the cardiovascular response to exercise in older adults with CHD is crucial for effective management.
Purpose of the Study:
- To investigate the cardiovascular system's response to exercise tolerance in patients over 75 with CHD.
- To evaluate the diagnostic significance of treadmill exercise test (TET) parameters in this demographic.
Main Methods:
- 110 patients underwent TET and coronary angiography.
- Patients were stratified into an elderly group (≥75 years) and a control group (<60 years).
Main Results:
- A higher proportion of elderly patients exhibited positive TET results compared to the control group.
- Elderly CHD patients demonstrated lower exercise time, peak heart rate, and earlier onset of ST depression during TET.
- No significant differences were observed in the extent or duration of ST depression between groups.
Conclusions:
- Treadmill exercise testing holds significant diagnostic value for identifying CHD in elderly individuals.
- Older patients with CHD exhibit diminished exercise endurance compared to younger counterparts.
Abstract:
To study the response of the cardiovascular system, to exercise tolerance in-patients over 75 years old with coronary heart disease (CHD), and to evaluate the significance of the parameters of the treadmill exercise test (TET). 110 patients received TET and coronary artery angiography. They were divided into two groups: the elderly patients group included 50 patients over 75 years old, and the control group included 60 patients under 60 years old. (1) With aging, there were much more CHD patients in the positive TET (P < 0.05) than in the negative TET (P > 0.05). (2) The parameters of TET for the elderly CHD patients group, included exercise time, peak heart rate, and the onset of ST depression, were lower than the control group (P < 0.05). There was no statistical significance between the two groups in the extent and duration of ST depression (P < 0.05). (1) In TET, the elderly patients had the higher diagnostic value on CHD. (2) The elderly patients with CHD had the lower endurance to exercise test.
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