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Ginkgo biloba for tinnitus.

Malcolm P Hilton1, Eleanor F Zimmermann, William T Hunt

  • 1ENT Department, Royal Devon and Exeter NHS Trust, Exeter, UK. malcolm.hilton@rdeft.nhs.uk.

The Cochrane Database of Systematic Reviews
|April 2, 2013
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Summary
This summary is machine-generated.

Ginkgo biloba does not effectively treat tinnitus when it is the main issue. While some minor improvements were noted in dementia patients, the overall evidence for tinnitus relief is limited.

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Area of Science:

  • Otolaryngology
  • Neurology
  • Pharmacology

Background:

  • Tinnitus, the perception of sound without external stimuli, lacks universally satisfactory treatments.
  • Ginkgo biloba is frequently suggested for tinnitus management, but placebo effects are significant.
  • This review is an update of previous Cochrane reviews on Ginkgo biloba for tinnitus.

Purpose of the Study:

  • To evaluate the efficacy of Ginkgo biloba in individuals experiencing tinnitus.
  • To assess Ginkgo biloba's impact on tinnitus as a primary complaint or a symptom of cerebral insufficiency.

Main Methods:

  • Searched multiple databases including Cochrane, PubMed, EMBASE, and Web of Science for relevant trials.
  • Included adults (18+) with tinnitus or cerebral insufficiency with tinnitus.
  • Independent data extraction and quality assessment by multiple authors for the 2012 update.

Main Results:

  • Four trials (1543 participants) with low risk of bias were analyzed.
  • No evidence supported Ginkgo biloba's effectiveness for tinnitus as a primary complaint.
  • A small, statistically significant reduction in tinnitus was observed in dementia patients, but clinical significance is uncertain.

Conclusions:

  • Limited evidence suggests Ginkgo biloba is not effective for tinnitus when it is the primary health concern.
  • Further research may be needed to clarify potential benefits in specific patient groups, such as those with dementia.