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Updated: May 12, 2026

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
[Associations between calcium intake and risk of cardiovascular disease]
Mitsumasa Umesawa1, Hiroyasu Iso
1Center for Medical Sciences, Ibaraki Prefectural University of Health Sciences, Ami, Ibaraki, Japan.
Abstract:
We reviewed epidemiologic evidence regarding the associations between dietary or supplementary calcium intake and risk of cardiovascular disease. Dietary calcium intake, especially from milk and dairy foods, was inversely associated with risk of stroke among Asians and American women, but not among American men and Europeans. Supplementary calcium intake was not associated with risk of stroke. As for coronary heart disease, dietary calcium intake was not associated with the risk in most of the previous studies. Supplementary calcium intake was positively associated with risk of coronary heart disease. In conclusion, dietary calcium intake may be beneficial for the prevention of stroke in Japanese whose average intake of calcium is low.
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