Related Experiment Video
Updated: May 12, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
Ocular ischemic syndrome: a classical presentation of an uncommon condition
Jayesh A Vazirani1, Zoramthara Zadeng, Mangat R Dogra
1Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Abstract:
We report a 47-year-old male who presented with acute mono-ocular vision loss, and had classical signs of global ocular ischemia in the right eye. Fundus fluorescein angiography demonstrated delayed choroidal filling and no perfusion of retinal vasculature. Carotid Doppler and computed tomogram (CT) angiography studies revealed extensive bilateral atherosclerotic disease involving the carotid circulation. Ophthalmologists must be aware of the possibility of this potentially fatal condition, which is extremely rare. An astute clinical diagnosis, targeted workup for systemic associations and a prompt referral may turn out to be life-saving.
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