Sex differences in cerebral palsy incidence and functional ability: a total population study

A Chounti1, G Hägglund, P Wagner

  • 1Euroclinic Children's Hospital, Lemesou, Athens, Greece.

Insights

Male sex is a risk factor for cerebral palsy (CP), with no detected equalization in CP incidence between boys and girls in recent years. Motor function levels showed no consistent sex differences.

Area of Science:

  • Pediatrics
  • Neurology
  • Epidemiology

Background:

  • Cerebral palsy (CP) affects motor function in children.
  • Understanding gender differences in CP is crucial for targeted interventions.

Purpose of the Study:

  • To investigate gender disparities in CP subtypes and motor function.
  • To analyze trends in CP incidence among boys and girls.

Main Methods:

  • Study included 590 children with CP born in southern Sweden (1990-2005).
  • CP classification used Surveillance of Cerebral Palsy in Europe, Gross Motor Function Classification System (GMFCS), and Manual Ability Classification System (MACS).
  • Poisson regression modeling analyzed CP incidence trends by birth year.

Main Results:

  • Male predominance observed across most GMFCS and MACS levels and CP subtypes, excluding ataxic CP.
  • No statistically significant gender differences found in gross motor function or manual ability.
  • CP incidence trends showed no change between boys and girls from 1990-2005.

Conclusions:

  • No equalization in CP incidence between genders observed in recent years.
  • Consistent sex differences in motor function levels were not confirmed.
  • Male sex identified as a risk factor for developing CP.
Abstract

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