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Updated: May 12, 2026
06:57
Puncture-Induced Iris Neovascularization as a Mouse Model of Rubeosis Iridis
Published on: March 8, 2018
[Iris tumor of unknown origin]
J Rueping1, A Klingenstein, J Wagener
1Augenklinik[Symbol: see text]der[Symbol: see text]LMU, Klinikum[Symbol: see text]der[Symbol: see text]Universität[Symbol: see text]München, Campus[Symbol: see text]Innenstadt, Mathildenstr.[Symbol: see text]8, 80336, München, Deutschland, Johann.Rueping@med.uni-muenchen.de.
Summary
A fungal infection caused an iris tumor and eye inflammation in a cancer patient. Treatment with voriconazole and surgery successfully resolved the ocular condition.
Area of Science:
- Ophthalmology
- Mycology
- Oncology
Background:
- A 51-year-old woman with a history of metastatic bowel cancer and ongoing chemotherapy presented with ocular symptoms.
- The patient exhibited a non-specific iris tumor and intraocular inflammation in the left eye.
Observation:
- Surgical excision of the iris lesion revealed fungal spores and hyphae.
- Microbiological analysis confirmed the presence of Candida albicans.
Findings:
- The patient was treated with both local and systemic voriconazole, an antifungal medication.
- A combined vitrectomy and cataract surgery was performed.
Implications:
- Successful management of ocular candidiasis in an immunocompromised patient.
- Highlights the importance of considering fungal infections in cancer patients with ocular inflammation.
