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[A case of non-functioning adrenocortical tumor].
11st Dept. of Surgery, Hokkaido Univ., School of Med.
Gan No Rinsho. Japan Journal of Cancer Clinics
|June 1, 1990
Summary
This case report details a large, non-functioning adrenal cortical adenocarcinoma successfully resected from the liver. The patient remained recurrence-free for over four years post-surgery, highlighting effective treatment for adrenal cancer.
Area of Science:
- Endocrinology
- Surgical Oncology
- Pathology
Background:
- Adrenocortical tumors are rare neoplasms originating from the adrenal cortex.
- Non-functioning tumors present diagnostic challenges, often discovered incidentally or upon reaching significant size.
- Adrenocortical adenocarcinoma is an aggressive malignancy requiring prompt diagnosis and management.
Observation:
- A patient presented with non-specific symptoms of fever and fatigue, initially suspected to be a liver tumor.
- Advanced imaging, including hepatic angiography, confirmed a right adrenal tumor.
- Despite significant size (10x12x18 cm, 1280g) and necrotic changes, endocrinal function tests were normal.
Findings:
- Pathological examination confirmed the diagnosis of adrenal cortical adenocarcinoma.
- Surgical resection included removal of adjacent diaphragm and liver tissue.
- Post-operative treatment with oral 5-fluorouracil (5-FU) was administered.
Implications:
- This case demonstrates the successful surgical management of a large, non-functioning adrenocortical adenocarcinoma.
- Complete resection and adjuvant chemotherapy can lead to long-term disease-free survival.
- Accurate diagnosis and multidisciplinary approach are crucial for managing complex adrenal tumors.