Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Smooth Endoplasmic Reticulum

Smooth Endoplasmic Reticulum

Smooth endoplasmic reticulum or smooth ER is a sub-organelle with specialized functions in animal cells and plant cells. It is often associated with the tubule morphology of the endoplasmic reticulum.
The ER provides optimal conditions for synthesizing steroid hormones and lipids, such as phospholipids and triglycerides. Traditionally, lipid metabolism was considered to be a smooth ER function. However, there is no direct evidence to prove that rough ER is completely excluded from lipid...

Endocrine Signaling

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.

Endocrine Signaling

Endocrine Signaling

Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

Structures of the Endocrine System

Structures of the Endocrine System

The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...

Cushing Syndrome I: Introduction

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Tet2 modulates ER stress responses related to β-cell death and autoimmunity in diabetes.

iScience·2026

Same author

Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes.

The Journal of clinical investigation·2024

Same author

Iron Deficiency Related to Obesity.

Journal of infusion nursing : the official publication of the Infusion Nurses Society·2024

Same author

Cryopreserved versus fresh peripheral blood allogeneic stem cell transplantation outcomes in patients receiving post-transplant cyclophosphamide for graft-versus-host prophylaxis during the COVID-19 pandemic: a single center experience.

International journal of hematology·2022

Same author

Indirect and Direct Effects of SARS-CoV-2 on Human Pancreatic Islets.

Diabetes·2022

Same author

The Impostor Phenomenon in Mental Health Professionals: Relationships Among Compassion Fatigue, Burnout, and Compassion Satisfaction.

Contemporary family therapy·2021

Search research articles

Related Experiment Video

Updated: May 12, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Multiple endocrine neoplasia syndromes.

¹Accredo Health Group, Inc. psclark220@comcast.net

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society

|April 6, 2013

Summary

Multiple endocrine neoplasia (MEN) syndromes are hereditary conditions causing various endocrine carcinomas. Early recognition by primary care providers is crucial for timely diagnosis and improved patient outcomes.

Area of Science:

Endocrinology
Genetics
Oncology

Background:

Multiple endocrine neoplasia (MEN) comprises hereditary carcinoma syndromes.
Autosomal dominant gene aberrations lead to endocrine carcinomas and anatomical abnormalities.
Delayed diagnosis in familial endocrine carcinoma patients significantly impacts morbidity and mortality.

Purpose of the Study:

To introduce the various types of MEN syndromes.
To highlight the critical role of infusion nurses in managing patients with MEN.
To emphasize the importance of recognizing familial endocrine carcinoma.

Main Methods:

Review of existing literature on MEN syndromes.
Discussion of clinical manifestations and genetic basis of MEN.

More Related Videos

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Published on: August 25, 2023

Related Experiment Videos

Last Updated: May 12, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Genetic Profiling and Genome-Scale Dropout Screening to Identify Therapeutic Targets in Mouse Models of Malignant Peripheral Nerve Sheath Tumor

Published on: August 25, 2023

Exploration of the nursing care specific to MEN patients and families.

Main Results:

Overview of distinct MEN syndromes (MEN1, MEN2A, MEN2B, MEN4).
Identification of common endocrine tumors and associated non-endocrine features.
Emphasis on the need for multidisciplinary care and genetic counseling.

Conclusions:

Accurate identification and understanding of MEN syndromes are essential.
Infusion nurses play a vital role in patient and family support and treatment administration.
Improved provider education can mitigate delays in diagnosis and treatment for MEN patients.