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Updated: May 12, 2026

Low-stress Route Learning Using the Lashley III Maze in Mice
Published on: May 22, 2010
This niche is a maze; an amazing niche
Maher Hanoun1, Paul S Frenette
1Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Abstract:
The cellular identity of niche cells that regulate hematopoietic stem cell (HSC) self-renewal and differentiation has been debated for several years. Two recent studies in Nature (Ding and Morrison, 2013; Greenbaum et al., 2013) have shed light into the bone marrow stromal subsets making CXCL12, a chemokine critical for HSC maintenance.
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