Related Experiment Video
Updated: May 12, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Takotsubo cardiomyopathy: natural history
1Cardiovascular Research Division, Minneapolis Heart Institute Foundation, 920 East 28th Street, Suite 620, Minneapolis, MN 55407, USA. scott.sharkey@allina.com
Insights
This review details takotsubo cardiomyopathy, distinguishing it from acute coronary syndrome. It covers clinical features, diagnostic findings, complications, and treatment for stress-induced heart muscle dysfunction.
Area of Science:
- Cardiology
- Internal Medicine
- Cardiovascular Diseases
Background:
- Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy, mimics acute coronary syndrome.
- Accurate diagnosis and management are crucial for patient outcomes.
Purpose of the Study:
- To comprehensively review the clinical features of takotsubo cardiomyopathy.
- To differentiate takotsubo cardiomyopathy from acute coronary syndrome.
- To discuss diagnostic findings, complications, and treatment strategies.
Main Methods:
- Literature review of clinical features, diagnostic modalities, and management of takotsubo cardiomyopathy.
- Analysis of characteristic findings on electrocardiogram, biochemical testing, and cardiac imaging.
- Review of reported complications and treatment approaches.
Main Results:
- Key clinical features distinguishing takotsubo cardiomyopathy from acute coronary syndrome are presented.
- Characteristic electrocardiogram, biochemical, and cardiac imaging findings are detailed.
- Common complications, including heart failure, arrhythmias, and ventricular thrombi, are discussed.
Conclusions:
- Takotsubo cardiomyopathy requires specific diagnostic criteria to differentiate it from acute coronary syndrome.
- Understanding its pathophysiology, complications, and treatment is essential for effective patient care.
- Long-term survival and proposed pathophysiological mechanisms are reviewed.
Abstract:
This article provides a comprehensive review of the clinical features of takotsubo (stress) cardiomyopathy. The author discusses key features that distinguish this cardiomyopathy from acute coronary syndrome. This review includes detail of characteristic findings on electrocardiogram, biochemical testing, and cardiac imaging, as well as complications including congestive heart failure, arrhythmia, ventricular thrombi, and left ventricular outflow obstruction. The review concludes with a discussion of the proper treatment, long-term survival, and proposed pathophysiology.
Related Concept Videos
Cardiomyopathy I: Introduction and Classification
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy II: Dilated Cardiomyopathy
Coronary Artery Disease II: Pathophysiology
Cardiomyopathy V: Interprofessional Care
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
