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Rapid induction of an immune response in rat Peyer's patch after oral administration of Enterococcus faecalis strain
Ryo Inoue1, Takamitsu Tsukahara, Noriko Matsukawa
1Kyoto Institute of Nutrition & Pathology, Kyoto, Japan.
Bioscience, Biotechnology, and Biochemistry
|April 9, 2013
Abstract:
A rapid and sharp immune response induced in Peyer's patches (PPs) by a single gavage of a heat-killed Enterococcus faecalis strain EC-12 (EC-12) was demonstrated. EC-12 was observed inside the PPs 2.5 h post administration and induction of TNF-α and CD69 gene expression was observed at the same time. The immune response in PPs disappeared 24 h post administration.
