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Updated: May 12, 2026

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Finding type 2 diabetes causal single nucleotide polymorphism combinations and functional modules from genome-wide

Chiyong Kang1, Hyeji Yu, Gwan-Su Yi

  • 1Department of Bio and Brain Engineering, KAIST, Daejeon 305-701, South Korea.

BMC Medical Informatics and Decision Making
|April 10, 2013
PubMed
Summary

Detecting causal SNP combinations for complex diseases like type 2 diabetes (T2D) is challenging due to low statistical power. This study introduces a novel method using optimal filtration and random forests to identify T2D causal SNP combinations and their biological significance.

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