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[Limbic encephalitis: a new paraneoplastic auto-immune manifestation associated with metastatic melanoma?]

C Becquart1, G Ryckewaert, E Desmedt

  • 1Service de dermatologie, hôpital Claude-Huriez, rue Michel-Polonovski, 59037 Lille cedex, France. coralie.becquart@univ-lille2.fr

Annales De Dermatologie Et De Venereologie
|April 10, 2013
PubMed
Abstract

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...