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Conjunctival Commensal Isolation and Identification in Mice

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

[Microbial structure of acute bacterial conjunctivitis].

D Chikviladze¹, N Nikuradze, Kh Gachechiladze

¹Tbilisi State Medical University, Department of Microbiology and Immunology, Tbilisi, Georgia.

Georgian Medical News

|April 10, 2013

Summary

Microbiological investigation revealed common bacteria in acute conjunctivitis cases. High antibiotic resistance necessitates individual microbiological analysis for effective treatment.

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Area of Science:

Ophthalmology
Microbiology
Infectious Diseases

Background:

Acute conjunctivitis is a common eye infection.
Microbial pathogens are the primary cause of acute conjunctivitis.
Understanding the local microbial spectrum and antibiotic resistance is crucial for effective treatment.

Purpose of the Study:

To identify the microbial spectrum of acute conjunctivitis in Tbilisi.
To determine the antibiotic sensitivity of isolated microorganisms.
To guide rational treatment strategies for acute conjunctivitis.

Main Methods:

Microbiological investigation of 124 patients with acute conjunctivitis.
Isolation and identification of bacterial strains using classic methods and API systems.
Antibiotic sensitivity testing (ciprofloxacin, levofloxacin, tobramicin, norfloxacin, moxifloxacin) via agar diffusion.

Main Results:

124 microbial strains were isolated, with Staphylococcus aureus being the most prevalent (28.2%).
Pseudomonas aeruginosa (19.4%), Moraxella catarrhalis (16.9%), and Haemophilus influenzae biogroup aegyptius (13.7%) were also frequently detected.
A high level of resistance to commonly used antibiotics in eye drops was observed.

Conclusions:

Microbiological investigation is recommended for each acute conjunctivitis case.
Tailored antibiotic selection based on sensitivity testing is essential for successful treatment.
The findings highlight the need for ongoing surveillance of antibiotic resistance patterns.