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Related Experiment Video

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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
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Published on: November 21, 2013

Familial psychogenic movement disorders.

Maria Stamelou1, Giovanni Cossu, Mark J Edwards

  • 1Sobell Department of Motor Neuroscience and Movement Disorders, University College London Institute of Neurology, London, United Kingdom; Department of Neurology, University of Athens, Attiko Hospital, Athens, Greece; Neurology Clinic, Philipps University, Marburg, Germany.

Movement Disorders : Official Journal of the Movement Disorder Society
|April 10, 2013
PubMed
Summary

Psychogenic (or functional) movement disorders (PMDs) can occur in families. A positive family history of PMDs may indicate a higher risk and warrants further investigation of affected relatives.

Keywords:
familial movement disordersfunctional movement disordersorganic movement disorderspsychogenic movement disorders

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Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Psychogenic (or functional) movement disorders (PMDs) are typically considered sporadic.
  • Limited research exists on familial clusters of PMDs.

Purpose of the Study:

  • To investigate the occurrence and characteristics of PMDs within families.
  • To determine if a family history influences the risk or presentation of PMDs.

Main Methods:

  • Identified 10 patients from 5 families with PMDs.
  • Described clinical characteristics, including videos and long-term follow-up.

Main Results:

  • Familial PMDs share clinical clues with sporadic cases.
  • Affected family members exhibited similar PMD phenomenology.
  • Phenomenology of PMDs was consistent within families.

Conclusions:

  • A positive family history does not exclude functional disorders.
  • Investigating family members is crucial when PMDs are suspected.
  • Family history of PMDs may be an independent risk factor.