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Updated: May 12, 2026

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Clinical management of diabetic ulcers
1Division of Geriatric Medicine, St Louis University Health Science Center, 1402 South Grand Boulevard, St Louis, MO 63104, USA. thomasdr@slu.edu
Abstract:
The presence of neuropathy is the most important factor in the development of a diabetic ulcer, whereas inadequate vascular supply is the most important factor in healing. Diabetic foot ulcers are complex wounds that require a long time to heal. A key element in treating diabetic wounds is to off-load, or remove, pressure from an insensate foot. Topical wound dressings are aimed at providing a moist wound environment. No single dressing has been shown to be superior to another. Clinical infections are common but probably overdiagnosed. The question of how much and how often a diabetic foot wound needs to be debrided is controversial.
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