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Dopaminergic afferents to the mesencephalic trigeminal nucleus of the rat: a light and electron microscope
J C Copray1, R S Liem, G J Ter Horst
1Department of Neurobiology and Oral Physiology, University of Groningen, The Netherlands.
Brain Research
|April 30, 1990
Abstract:
The localization and sources of dopaminergic projections on the primary afferent neurons in the mesencephalic trigeminal nucleus (Me5) of the rat were studied using light and electron microscopic immunocytochemical staining techniques combined with anterograde and retrograde neuroanatomical tract tracing methods. Me5 neurons were found to receive a dopaminergic input that is part of a dopaminergic fibre plexus extending over the neighbouring nucleus parabrachialis and locus coeruleus. These dopaminergic afferents originate from the substantia nigra, the ventral tegmental area and the medial hypothalamus.