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Updated: May 12, 2026

Quantitative Analysis of Viscoelastic Properties of Red Blood Cells Using Optical Tweezers and Defocusing Microscopy

Quantitative Analysis of Viscoelastic Properties of Red Blood Cells Using Optical Tweezers and Defocusing Microscopy

Published on: March 25, 2022

Blood viscometer applying electromagnetically spinning method.

Kazuyoshi Fukunaga¹, Masaya Onuki, Yoshinori Ohtsuka

¹Department of Clinical Engineering, Faculty of Health Sciences, Kyorin University, 476 Miyashitacho, Hachioji, Tokyo, 192-8508, Japan, fukunaga@ks.kyorin-u.ac.jp.

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs

|April 12, 2013

Summary

This summary is machine-generated.

A new electromagnetically spinning (EMS) viscometer easily measures blood viscosity. This device accurately determines blood viscosity, crucial for understanding hemodynamics in extracorporeal circulation and cardiac support.

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Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

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Published on: January 12, 2018

Area of Science:

Biomedical Engineering
Fluid Dynamics

Background:

Blood viscosity is critical for hemodynamics in extracorporeal circulation and cardiac support.
Accurate viscosity measurements are essential for clinical applications.

Purpose of the Study:

To develop a novel, easy-to-use viscometer utilizing the electromagnetically spinning (EMS) method.
To measure blood viscosity accurately for clinical relevance.

Main Methods:

Developed an EMS viscometer using Lorentz force to rotate a 2 mm aluminum ball within a 0.3 ml sample.
Calibrated the viscometer using known viscosity liquids and computational fluid dynamics.
Evaluated performance with silicone oil and measured bovine blood viscosity at varying hematocrit levels.

Main Results:

The EMS viscometer demonstrated accurate performance, measuring silicone oil viscosity at 9.55 ± 0.10 mPa s.
Bovine blood viscosity measurements followed Casson's equation.
Observed Newtonian behavior in silicone oil and shear-thinning in bovine blood.

Conclusions:

The developed EMS viscometer is effective for measuring blood viscosity.
The device shows potential for clinical applications, particularly at the bedside.
Accurate blood viscosity data can aid in managing extracorporeal circulation and cardiac support.