Related Experiment Video
Updated: May 12, 2026

Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser
Published on: May 5, 2020
[New understanding of dog's prostatic urethral re-epithelial underwent two-micron laser prostatic vaporesection]
Guang-heng Luo1, Lei Luo, Xiu-shu Yang
1Department of Urology, Guizhou Provincial People's Hospital, Guiyang 550002, China.
Objective:
To study the re-epithelialization of dog's prostate urethra after two-micron laser resection of the prostate (TmLRP) and the role of CK34 (CK34βE12)-positive cells in this process.
Methods:
TmLRP were performed in 15 elder male dogs and wound specimens harvested at Days 3, 7 and 14 respectively. Immunohistochemical staining was performed to determine the expression levels of CK34 and prostate specific antigen (PSA) in prostatic urethra urothelial cells.
Results:
There was no CK34-positive cells in surgical wounds after 3 days while a cluster of CK34-positive cells were found to cover surgical wounds after 7 days, and these cells attached to residual prostate tissues. At Day 14 post-operation, positive expression of CK34 was found in basal cells of newborn urothelium.
Conclusion:
Prostate tissues are the important organizations for re-epithelialization of prostatic urethra after benign prostate hyperplasia surgery, and CK34-positive basal cells play an important role in this process.
Related Concept Videos
Urologic Endoscopic Procedure: Cystoscopic Examination
Urinary Tract Calculi VI: Surgical Management
Anatomy of the Genitourinary System II: Bladder and Urethra

