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Published on: December 20, 2024
Laparoscopic splenic biopsy--porcine to human studies--using a fibrin sealant technique
Kei Yiu Douglas Hui1, Stuart M Robinson, Aimen Amer
1Department of Hepatopancreatobiliary and Transplantation Surgery, The Freeman Hospital, Newcastle Upon Tyne, Tyne and Wear, UK. kei-yiu.hui@newcastle.ac.uk
Introduction:
Splenic biopsies are not routinely performed because of the risk of severe hemorrhage. The aim of this study was to explore the feasibility of performing laparoscopic splenic biopsies using a fibrin sealant in pigs and then to translate this technique into the clinical setting.
Method:
Four German Landrace pigs underwent a laparoscopic splenic biopsy using a fibrin sealant to occlude the needle tract. Time to achieve hemostasis and postoperative hemorrhage were assessed.
Result:
The average time to achieve haemostasis was 15 s (range, 8 to 25 s) with no hemorrhage from the needle tract observed. Subsequently this was translated into the clinical setting where a patient also underwent a laparoscopic splenic biopsy without any adverse effect.
Conclusions:
Laparoscopic splenic biopsy with the application of a fibrin sealant is a safe and efficient technique.
