Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

SBAR II: Application of SBAR01:14

SBAR II: Application of SBAR

SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR I: Understanding the Concept01:29

SBAR I: Understanding the Concept

Effective communication among healthcare professionals during hand-off reporting is essential to delivering safe and continuous patient care. Common professional interactions include reports to healthcare team members, hand-off, and transfer reports. Nurses routinely report information to other healthcare team members and also urgently contact healthcare providers to report changes in patient status.
Standardized methods of communication have been developed to ensure that information is...
Archival Research01:40

Archival Research

Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of guinea pig data to obtain starting points for skin sensitisation risk assessment - A commentary.

Regulatory toxicology and pharmacology : RTP·2024
Same author

The inter-laboratory validation study of EpiSensA for predicting skin sensitization potential.

Journal of applied toxicology : JAT·2023
Same author

Assessing the risk of induction of skin sensitization to plant protection products: A quantitative approach.

Regulatory toxicology and pharmacology : RTP·2023
Same author

Proteolytic activity accelerates the T<sub>H</sub>17/T<sub>H</sub>22 recall response to an epicutaneous protein allergen-induced T<sub>H</sub>2 response.

Journal of immunotoxicology·2022
Same author

Perforin, COVID-19 and a possible pathogenic auto-inflammatory feedback loop.

Scandinavian journal of immunology·2021
Same author

Epicutaneous challenge with protease allergen requires its protease activity to recall T<sub>H</sub>2 and T<sub>H</sub>17/T<sub>H</sub>22 responses in mice pre-sensitized via distant skin.

Journal of immunotoxicology·2021

Related Experiment Video

Updated: May 12, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
07:40

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Published on: April 28, 2022

The research programme of SCAAT.

Odile de Silva1, David Basketter,

  • 1COLIPA, rue de Congrès 5-7, 1000 Brussels, Belgium. odesilva@recherche.loreal.com

Alternatives to Laboratory Animals : ATLA
|April 16, 2013
PubMed
Summary

The Cosmetics Industry is developing new non-animal testing methods for skin and eye irritation. These research projects focus on optimizing in vitro techniques for chemical safety assessments.

Area of Science:

  • Cosmetic Science
  • Toxicology
  • In Vitro Methods

Background:

  • The European Federation of the Cosmetics Industry (COLIPA) Steering Committee on Alternatives to Animal Testing (SCAAT) is addressing the need for reliable alternatives to animal testing.
  • Research efforts are concentrated on skin tolerance and eye irritation endpoints, crucial for cosmetic product safety.

Purpose of the Study:

  • To develop and optimize alternative, non-animal testing methods for skin sensitization, skin irritation, and eye irritation.
  • To identify novel biomarkers and endpoints predictive of chemical-induced skin and eye damage.
  • To advance the prevalidation of these alternative methods for regulatory acceptance.

Main Methods:

  • Skin sensitization projects involve standardizing and optimizing methods using human dendritic cells and identifying gene expression changes.

More Related Videos

Implementation of a Coherent Anti-Stokes Raman Scattering (CARS) System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope
12:54

Implementation of a Coherent Anti-Stokes Raman Scattering (CARS) System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope

Published on: July 17, 2016

Quantitatively Measuring In situ Flows using a Self-Contained Underwater Velocimetry Apparatus (SCUVA)
09:22

Quantitatively Measuring In situ Flows using a Self-Contained Underwater Velocimetry Apparatus (SCUVA)

Published on: October 31, 2011

Related Experiment Videos

Last Updated: May 12, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
07:40

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay

Published on: April 28, 2022

Implementation of a Coherent Anti-Stokes Raman Scattering (CARS) System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope
12:54

Implementation of a Coherent Anti-Stokes Raman Scattering (CARS) System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope

Published on: July 17, 2016

Quantitatively Measuring In situ Flows using a Self-Contained Underwater Velocimetry Apparatus (SCUVA)
09:22

Quantitatively Measuring In situ Flows using a Self-Contained Underwater Velocimetry Apparatus (SCUVA)

Published on: October 31, 2011

  • Skin irritation research utilizes genomic and proteomic technologies to discover new irritation markers.
  • Eye irritation studies focus on identifying in vitro endpoints, including corneal responses and recovery kinetics, to predict in vivo outcomes in collaboration with university ophthalmologists.

    • Main Results:

    • Ongoing projects are actively developing and refining in vitro methodologies for assessing skin and eye toxicity.
    • Identification of potential new biomarkers for skin irritation is being pursued through advanced molecular technologies.
    • Exploration of corneal physiological changes in vitro aims to establish predictive models for eye irritation.

    Conclusions:

    • The COLIPA SCAAT initiative is making progress in establishing robust alternative testing strategies for cosmetic ingredients and products.
    • These industry-led projects are crucial for reducing and replacing animal testing in the cosmetics sector.
    • The research aims to provide validated in vitro methods for assessing chemical safety, enhancing both ethical considerations and scientific rigor.