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Updated: May 12, 2026
03:32
Measurement of Chitinase Activity in Biological Samples
Published on: August 22, 2019
Chitinases and lung diseases
Serap Duru1, Melike Yüceege, Sadık Ardıç
1Clinic of Chest Diseases, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. akcalis@hotmail.com
Tuberkuloz Ve Toraks
|April 16, 2013
Summary
Human chitinases, enzymes that break down chitin, are present despite no natural chitin in the body. This review explores their potential roles in lung diseases and immune responses.
Area of Science:
- Biochemistry
- Immunology
- Pulmonology
Background:
- Chitinase enzymes are expressed in humans, though endogenous chitin is absent.
- The precise pathophysiological roles of chitinases in humans remain largely unknown.
- Emerging evidence suggests chitinases are involved in immune and inflammatory processes.
Purpose of the Study:
- To review the current literature on the role of chitinases in human lung diseases.
- To investigate the potential involvement of chitinases in immune and inflammatory responses within the lungs.
Main Methods:
- Literature review of existing studies on chitinases and lung diseases.
- Analysis of research exploring chitinase involvement in immune and inflammatory pathways.
Main Results:
- Chitinases may play a significant role in the pathogenesis of various lung conditions.
- Evidence links chitinase activity to immune modulation and inflammatory responses in the respiratory system.
Conclusions:
- Chitinases represent a potential therapeutic target for managing lung diseases.
- Further research is warranted to fully elucidate the function of chitinases in human respiratory health and disease.
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