Related Experiment Video
Updated: Jan 5, 2026
06:01
Semi-Automated Analysis of Peak Amplitude and Latency for Auditory Brainstem Response Waveforms Using R
Published on: December 9, 2022
2.8K
The effect of hypoxia on hearing function
Nevreste Didem Sonbay Yılmaz1, Cem Saka2, Burcu Oktay Arslan3
1Department of Ear, Nose, and Throat, Antalya Education and Training Hospital, Antalya, Turkey
Turkish Journal of Medical Sciences
|October 26, 2019
Summary
Hypoxia negatively impacts hearing function in COPD patients, affecting auditory brainstem response and otoacoustic emissions. However, the specific critical oxygen level that causes hearing impairment remains undetermined.
Area of Science:
- Audiology
- Pulmonology
- Otolaryngology
Background:
- Chronic Obstructive Pulmonary Disease (COPD) is associated with various systemic complications.
- Hypoxia, a common feature of COPD, may affect auditory function.
- Understanding the relationship between oxygen levels and hearing is crucial for patient management.
Purpose of the Study:
- To determine the critical partial oxygen pressure (pO2) threshold that impairs hearing function.
- To evaluate the effects of hypoxia on hearing in patients with COPD.
- To investigate potential audiological changes associated with reduced oxygen levels in COPD.
Main Methods:
- A case-control study comparing COPD patients with a healthy control group.
- Audiological assessments including distortion-product otoacoustic emissions (DPOAE) and auditory brainstem response (ABR).
- Patients were stratified based on partial oxygen pressure (pO2) levels.
Main Results:
- A statistically significant difference in DPOAE was observed between COPD patients and controls (P < 0.001).
- Hypoxia was linked to hearing threshold decline, poorer DPOAE results, and prolonged I-V interpeak latency in ABR.
- A precise critical pO2 level for hearing disruption could not be identified.
Conclusions:
- Hypoxia in COPD patients contributes to hearing impairment.
- Deterioration in hearing function is evident with reduced oxygen levels.
- Further research is needed to pinpoint the exact critical pO2 for audiological damage.
Related Concept Videos
01:23Hypoxia
1.8K
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
1.8K
01:21Acute Respiratory Failure-II
969
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
969
01:27Oxygen Transport in the Blood
5.6K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
5.6K
01:19Respiratory Assessment: Purpose and Indications
1.6K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.6K
01:24Factors Affecting Respiration
8.8K
Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
8.8K
01:16Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
529
Oxygen therapy has emerged as a significant tool in enhancing the quality of life for patients suffering from pulmonary arterial hypertension (PAH). While this therapy has principally been studied on patients with significant hypoxemia, this therapeutic approach helps prevent potential organ damage and can be administered in the comfort of one's home.
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
529