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Highly Sensitive and Rapid Fluorescence Detection with a Portable FRET Analyzer
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Published on: October 1, 2016

Highly selective fluorescence turn-on sensor for fluoride detection.

Binglin Sui1, Bosung Kim, Yuanwei Zhang

  • 1Department of Chemistry, University of Central Florida, Orlando, Florida 32816, USA.

ACS Applied Materials & Interfaces
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Researchers developed a novel fluorescent sensor for detecting fluoride ions. This sensor utilizes a unique C-H bond interaction, enabling selective and sensitive fluoride detection in water.

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Area of Science:

  • Supramolecular Chemistry
  • Analytical Chemistry
  • Materials Science

Background:

  • Triazole and triazolium compounds are known to interact with anions via hydrogen bonding.
  • C-H···anion interactions offer a pathway for developing novel sensing mechanisms.
  • Selective detection of fluoride is crucial for environmental monitoring and public health.

Purpose of the Study:

  • To demonstrate fluoride-induced deprotonation of a C-H bond for sensing applications.
  • To develop a highly selective fluorescence turn-on sensor for fluoride detection.
  • To assess the sensor's performance in aqueous media for practical fluoride monitoring.

Main Methods:

  • Synthesis of a fluorene-triazolium based fluorescent probe.
  • Investigation of C-H···F(-) interactions using fluorescence spectroscopy.
  • Characterization of the binding mechanism via (1)H NMR titrations.
  • Preparation of test papers for practical fluoride detection.

Main Results:

  • Evidence of fluoride-induced deprotonation of the C-H bond was observed.
  • The developed sensor exhibited a highly selective fluorescence turn-on response to fluoride.
  • The sensor detected fluoride in aqueous solutions down to 1.9 ppm.
  • Successful application in preparing test papers for fluoride estimation in drinking water.

Conclusions:

  • The C-H bond in the fluorene-triazolium system can be selectively deprotonated by fluoride.
  • A novel fluorescence turn-on sensor for fluoride detection based on this principle has been successfully developed.
  • The sensor demonstrates potential for practical, on-site monitoring of fluoride levels in drinking water.