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Knee Joint

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...

Bones of the Lower Limb: Femur and Patella

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the neck...

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Updated: May 12, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Knee replacement for osteoarthritis.

Alexander D Liddle¹, Elise C Pegg, Hemant Pandit

¹Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, University of Oxford, United Kingdom.

|April 16, 2013

Summary

This summary is machine-generated.

Total knee replacement (TKR) is a common surgery for knee osteoarthritis, offering good outcomes. However, patient dissatisfaction highlights the need to understand factors influencing TKR success and explore alternatives.

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Last Updated: May 12, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

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Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Area of Science:

Orthopedic Surgery
Rheumatology
Geriatric Medicine

Background:

Knee replacement is a prevalent surgical procedure for older adults, with rising incidence.
Total knee replacement (TKR) is the primary curative treatment for knee osteoarthritis, demonstrating overall positive outcomes regarding reoperation rates, functional results, and cost-effectiveness.
A notable percentage of patients report dissatisfaction post-TKR, prompting research into predictors of adverse outcomes.

Purpose of the Study:

To review the role of total knee replacement (TKR) in managing osteoarthritis.
To examine operative and non-operative alternatives to TKR.
To explore outcome measurement methods and the impact of patient and surgical factors on TKR success.

Main Methods:

Literature review focusing on total knee replacement (TKR) for osteoarthritis.
Analysis of studies on patient and surgical factors influencing TKR outcomes.
Examination of various outcome assessment methodologies in TKR.

Main Results:

Total knee replacement (TKR) is effective for knee osteoarthritis but patient dissatisfaction exists.
Factors influencing TKR outcomes include patient-specific characteristics and surgical techniques.
Diverse methods exist for measuring TKR success, impacting reported outcomes.

Conclusions:

Total knee replacement (TKR) remains a key treatment for knee osteoarthritis, but patient satisfaction is not universal.
Understanding patient and surgical variables is crucial for optimizing TKR outcomes.
Further research into predictors of dissatisfaction and alternative treatments is warranted.