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Updated: May 12, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Squamous cell carcinoma developing after CO2 laser resurfacing
Fabio Nicoli1, Alberto Balzani, Pietro Gentile
1Department of Plastic and Reconstructive Surgery, Policlinico Casilino, University of Tor Vergata in Rome, Italy. dr.fabionicoli@gmail.com
Background:
Skin resurfacing with the carbon dioxide (CO(2)) laser is currently a popular means of improving rhytides and scars and has been reported useful in the treatment for photodamaged skin, including precancerous and benign skin lesions, as well as superficial benign pigmented lesions.
Methods:
We describe a 68-year-old man who developed rapid squamous cell carcinoma (SCC) on the resurfaced areas 3 weeks following CO(2) laser resurfacing.
Results:
Rapid occurrence of SCC should be considered a rare complication, and we recommend carefully considering CO(2) laser resurfacing after excision of an SCC and surveying any cancer recurrences.
Conclusions:
We report a rare complication of CO(2) laser resurfacing. This report suggests that additional work in this area is warranted.
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