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Updated: May 12, 2026
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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
High priority future research needs for obstructive sleep apnea diagnosis and treatment
Kamal Patel1, Denish Moorthy, Jeffrey A Chan
1Institute of Clinical Research and Health Policy Studies, Tufts University School of Medicine, Tufts Medical Center, Boston, MA, USA.
Summary
Future research on obstructive sleep apnea (OSA) should prioritize key areas like cost-effectiveness and treatment compliance. Focusing on these critical topics will improve OSA management and patient outcomes.
Area of Science:
- Sleep Medicine
- Health Services Research
- Clinical Research Prioritization
Background:
- Obstructive sleep apnea (OSA) diagnosis and treatment require focused research.
- Existing research gaps hinder optimal patient care and management strategies.
Purpose of the Study:
- To identify and prioritize future research needs (FRN) for obstructive sleep apnea (OSA).
- To guide research efforts toward high-impact topics in OSA diagnosis and treatment.
Main Methods:
- A multi-stakeholder panel (patients, providers, payers, policymakers, investigators) was convened.
- Stakeholders nominated and prioritized FRN topics based on established criteria.
- Potential study designs were developed for the highest-priority topics.
Main Results:
- Thirty-seven topics were discussed and prioritized.
- Nine highest-priority FRN topics were identified, including cost-effectiveness, diagnostic criteria, preoperative screening, specialist involvement, prediction rules, treatment effects on long-term outcomes, alternative treatments, compliance strategies, and severity-outcome associations.
Conclusions:
- Refocusing research on prioritized questions is crucial for OSA management.
- Efforts should shift from simple short-term outcome comparisons to addressing complex, high-priority research needs.
- Prioritized research will benefit OSA patients, healthcare providers, and society.
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