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![Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59557.jpg&w=3840&q=50)
Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941
Published on: April 28, 2019
Production of [11C]CO2 with gas target at low proton energies
Francesc Sansaloni1, Juan Ignacio Lagares, Jordi Llop
1Medical Applications Unit, Technology Department, CIEMAT, Madrid, Av. Complutense 40, 28040 Madrid, Spain. francesc.sansaloni@ciemat.es
Abstract:
Nowadays the demand and the installation of self-shielded low-energy cyclotrons is growing, allowing the use of (11)C in many more centers. The aim of this study was the design of a new target and the evaluation of the production of (11)C as [(11)C]CO2 at low proton energies. The target was coupled to an IBA Cyclone-18/9 and the energy was decreased to 4-16 MeV. The newly designed target allowed the production of [(11)C]CO2 at different proton energies, and the results suggest that the cyclotron energy of Cyclone-18/9 is slightly higher than the nominal 18 MeV.
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