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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Cardiac thrombi mistaken for metastasis in recurrent melanoma

Leonarda Galiuto1, Gabriella Locorotondo, Elisa Fedele

  • 1Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy.

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|April 17, 2013
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...