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Updated: May 12, 2026
09:44
Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
[Hereditary hearing loss: Part 1: diagnostic overview and practical advice]
1Klinik für Hals-Nasen-Ohren-Heilkunde, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. Burke.William@MH-Hannover.de
HNO
|April 17, 2013
Summary
Congenital hearing loss affects 1-5 in 1000 children, with genetics implicated in 50-70% of cases. This article guides genetic testing decisions for non-syndromic and syndromic hearing loss.
Area of Science:
- Genetics
- Otolaryngology
- Medical Diagnostics
Context:
- Congenital hearing loss is a common birth defect, impacting 1-5 per 1000 newborns.
- Genetic factors are suspected in 50-70% of congenital hearing loss cases.
- Over 130 genetic loci are linked to hearing loss, with ongoing gene discovery.
Purpose:
- To provide insight into the complexities of genetic hearing loss.
- To guide decision-making for genetic testing in patients with hearing loss.
- To differentiate between non-syndromic and syndromic forms of genetic hearing loss.
Summary:
- Hearing loss is the most common congenital sensory defect.
- Genetic mutations are a significant cause of congenital hearing loss.
- Genetic testing is crucial for diagnosis and management, with over 130 identified loci.
Impact:
- Informs clinical practice regarding genetic testing protocols for hearing loss.
- Highlights the substantial economic and societal burden of deafness.
- Facilitates personalized medicine approaches for hearing loss treatment.
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