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Published on: June 1, 2011
A squaric acid-stimulated electrocatalytic reaction for sensing biomolecules with cycling signal amplification
Wenqiang Lai1, Dianping Tang, Libing Fu
1Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, PR China.
Abstract:
Squaric acid, a 2-dimensional planar structure of squarate C4O4 units linked by protons in a layered sheet, was utilized for the first time as a catalytic substrate for ultrasensitive electronic determination of low-abundance proteins by coupling a target-induced electrocatalytic reaction with the in situ cycling signal amplification strategy.
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