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Updated: May 12, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Complex inheritance for susceptibility to sudden cardiac death.

Raha Pazoki1, Michael W T Tanck, Arthur A M Wilde

  • 1Department of Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center Amsterdam (AMC), PO Box 22660, 1100 DD Amsterdam, The Netherlands. r.pazoki@amc.uva.nl.

Current Pharmaceutical Design
|April 18, 2013
PubMed
Summary

Sudden cardiac death (SCD) risk is influenced by heritable factors. Genome-wide association studies are identifying genetic variants that increase the risk of SCD, particularly during myocardial infarction.

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