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Related Experiment Video

Updated: Dec 18, 2025

Comprehensive Workflow of Mass Spectrometry-based Shotgun Proteomics of Tissue Samples
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Orbitrap mass spectrometry.

Roman A Zubarev1, Alexander Makarov

  • 1Division of Molecular Biometry, Department of Medicinal Biochemistry & Biophysics, Karolinska Institutet, Scheelesväg 2, SE 17177, Stockholm, Sweden. Roman.Zubarev@ki.se

Analytical Chemistry
|April 18, 2013
PubMed
Summary
This summary is machine-generated.

The Orbitrap analyzer offers high-resolution mass spectrometry with a compact design. It provides excellent speed and quantification for various analytical tasks.

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Area of Science:

  • Analytical Chemistry
  • Mass Spectrometry Instrumentation

Background:

  • High-resolution mass spectrometry is crucial for detailed chemical analysis.
  • Existing mass analyzers have limitations in speed, resolution, or size.

Purpose of the Study:

  • Introduce the Orbitrap, a novel high-resolution mass spectrometry analyzer.
  • Highlight its design, speed, and quantification capabilities.

Main Methods:

  • Description of the Orbitrap analyzer's innovative miniature design.
  • Evaluation of its performance in analytical applications.

Main Results:

  • The Orbitrap demonstrates high-resolution mass analysis capabilities.
  • It exhibits favorable speed and excellent quantification properties.
  • Its miniature design offers advantages in certain applications.

Conclusions:

  • The Orbitrap represents a significant advancement in mass spectrometry technology.
  • Its unique combination of features makes it suitable for diverse analytical challenges.
  • It favorably ranks among existing high-resolution mass analyzers.