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Updated: May 12, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
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Published on: January 18, 2018

Persistent postsurgical pain.

Roman Cregg1, Sibtain Anwar, Paul Farquhar-Smith

  • 1The Royal Marsden NHS Foundation Trust, London, UK.

Current Opinion in Supportive and Palliative Care
|April 18, 2013
PubMed
Summary
This summary is machine-generated.

Persistent postsurgical pain (PPP) affects many, yet awareness and treatment remain limited. Identifying and reducing risk factors is key to preventing this common issue after surgery.

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Area of Science:

  • Pain Medicine
  • Oncology
  • Surgical Outcomes

Background:

  • Persistent postsurgical pain (PPP) is a significant cause of morbidity, with a growing evidence base particularly for cancer surgery.
  • Historically, recognition and acceptance of PPP by patients and practitioners have been challenging.
  • This review addresses the increasing prevalence of PPP and its impact.

Purpose of the Study:

  • To raise awareness of the growing epidemic of persistent postsurgical pain.
  • To review the evidence for diagnosis, risk factors, prevention, and treatment of PPP, with a focus on cancer surgery.
  • To synthesize current evidence and identify gaps in knowledge.

Main Methods:

  • Comprehensive literature review and evidence synthesis.
  • Analysis of existing data on PPP prevalence, risk factors, and management strategies.
  • Focus on recent findings and identification of areas requiring further research.

Main Results:

  • An estimated 40,000 UK patients develop PPP annually, with 5-10% experiencing severe pain.
  • Lack of clear definition and awareness hinder PPP diagnosis and treatment access.
  • Several risk factors for PPP have been identified, suggesting potential preventive measures.

Conclusions:

  • Effective treatments for PPP are limited, highlighting a need for more research.
  • Reducing identified risk factors may help prevent the development of PPP.
  • More high-quality, large-scale controlled trials are essential to advance PPP management.