Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Dependence

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...

Stimulants

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...

CNS Depressants: Alcohol and Nicotine

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...

Drugs Acting on Autonomic Ganglia: Stimulants

Drugs Acting on Autonomic Ganglia: Stimulants

Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...

Chronic Obstructive Pulmonary Disease II: Emphysema

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cannabis Vaping, Smoking, and Dual Use and the Onset of Respiratory Symptoms Among U.S. Young Adults.

American journal of preventive medicine·2026

Same author

Society for Research on Nicotine and Tobacco Europe Debate: Mandated reduction of nicotine in tobacco products is not the logical next step.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco·2026

Same author

Averted lung cancer deaths due to reductions in cigarette smoking in the United States, 1970-2022.

CA: a cancer journal for clinicians·2025

Same author

Transformation of the tobacco product market in Japan, 2011-2023.

Tobacco control·2024

Same author

Kids No Longer Smoke Cigarettes. Why Aren't We Celebrating?

American journal of public health·2024

Same author

Cigarette Smoking Relapse Among People Who Switched to E-cigarettes or Other Tobacco Products.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco·2024

Search research articles

Related Experiment Video

Updated: May 12, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

An endgame for tobacco?

Kenneth E Warner

Tobacco Control

|April 18, 2013

Summary

This summary is machine-generated.

Tobacco control has reduced disease and death, but smoking remains a leading cause of preventable death. This paper explores novel "endgame" strategies to accelerate the end of tobacco use globally.

More Related Videos

Transcript and Metabolite Profiling for the Evaluation of Tobacco Tree and Poplar as Feedstock for the Bio-based Industry

Transcript and Metabolite Profiling for the Evaluation of Tobacco Tree and Poplar as Feedstock for the Bio-based Industry

Published on: May 16, 2014

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

Related Experiment Videos

Last Updated: May 12, 2026

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations

Published on: January 10, 2015

Transcript and Metabolite Profiling for the Evaluation of Tobacco Tree and Poplar as Feedstock for the Bio-based Industry

Transcript and Metabolite Profiling for the Evaluation of Tobacco Tree and Poplar as Feedstock for the Bio-based Industry

Published on: May 16, 2014

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol

Published on: January 18, 2018

Area of Science:

Public Health
Epidemiology
Health Policy

Background:

Tobacco control efforts since the 1960s have yielded significant successes in reducing tobacco-related morbidity and mortality.
Despite progress, cigarette smoking persists as the leading global cause of preventable premature death, with slow declines in developed nations and increases in low- and middle-income countries.
Current evidence-based policies are insufficient to rapidly decrease smoking prevalence.

Discussion:

The persistent burden of tobacco use necessitates the exploration of innovative and potentially radical "endgame" strategies.
This paper aims to identify and analyze principal tobacco endgame proposals.
The goal is to foster a broader and deeper conversation within the tobacco control community regarding these strategies.

Key Insights:

Novel "endgame" strategies are gaining traction due to the limitations of existing tobacco control policies.
A shared vision exists within the tobacco control community for a future free from tobacco's toll.
Divergent perspectives on the feasibility and implementation of endgame strategies currently exist.

Outlook:

Continued research and dialogue are crucial for advancing tobacco endgame strategies.
Engaging the broader tobacco control community is essential for developing effective endgame solutions.
The ultimate objective is to achieve a world without tobacco-related disease and death.