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Proteomics

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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Related Experiment Video

Updated: May 12, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Clinical proteomics stretch goals: EuPA 2012 roundtable report.

S E O'Neil¹, M J Palviainen, S Ten Have

¹Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg, Sweden.

Journal of Proteomics

|April 20, 2013

Summary

This summary is machine-generated.

Clinical proteomics faces challenges in understanding human diseases. This report outlines key discussion points and future goals for advancing clinical proteomic studies.

Keywords:

Biomarkers Clinical proteomics Stretch goals

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Published on: May 8, 2021

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Last Updated: May 12, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

Proteomic Profile of EPS-Urine through FASP Digestion and Data-Independent Analysis

Published on: May 8, 2021

Area of Science:

Clinical Proteomics
Human Disease Research
Biomarker Discovery

Background:

Clinical proteomics aims to improve human disease understanding and management.
Significant challenges hinder the progress of clinical proteomic studies.
A roundtable discussion was held at the European Association for Proteomics (EuPA) conference in 2012.

Purpose of the Study:

To discuss the challenges in clinical proteomics.
To identify key areas for successful clinical proteomic research.
To establish future goals for the field.

Main Methods:

Roundtable discussion among clinical proteomics researchers.
Identification and summarization of key discussion topics.
Formulation of stretch goals for the field.

Main Results:

Key challenges in clinical proteomics were identified.
Critical areas for successful proteomic studies were highlighted.
Specific future research goals were defined.

Conclusions:

Overcoming current challenges is crucial for advancing clinical proteomics.
The identified goals provide a roadmap for future research.
Collaboration and focused efforts are needed to realize the potential of clinical proteomics.