Related Experiment Video
Updated: May 12, 2026
06:08
Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
Nasal gout presenting as nasal obstruction.
Paul E Kwak1, Blythe K Gorman, Krista L Olson
1Bobby R. Alford Department of Otolaryngology–Head and Neck Surgery, Baylor College of Medicine, Houston, TX 77005, USA.
JAMA Otolaryngology-- Head & Neck Surgery
|April 20, 2013
Summary
Nasal gout, a rare cause of nasal obstruction, was identified in a patient with a history of trauma and sleep apnea. Surgical removal of the gouty tophus relieved symptoms, improving breathing and sleep.
Area of Science:
- Otorhinolaryngology
- Rheumatology
- Pathology
Background:
- Nasal obstruction is a common complaint with diverse etiologies.
- Gout, a form of inflammatory arthritis, rarely manifests in the nasal structure.
Observation:
- A 56-year-old male patient presented with persistent nasal obstruction and congestion, unresponsive to medical management.
- Physical examination revealed severe septal deviation, nasal valve collapse, and a suspicious dorsal nasal mass.
- Surgical exploration during septorhinoplasty identified a significant mass on the nasal dorsum.
Findings:
- Histopathological analysis confirmed the nasal mass to be a gouty tophus.
- The tophus extended from the nasal dorsum to the tip and into the septal plane.
Implications:
- This case highlights gout as a rare but important differential diagnosis for nasal obstruction.
- Accurate diagnosis and surgical intervention can significantly improve patient outcomes for nasal obstruction caused by gouty tophi.
Related Concept Videos
01:24Nose and Nasal Cavity
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
01:30Epistaxis
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
01:29Suctioning the Nasopharyngeal Airway
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
01:27Upper Respiratory Drugs: Decongestants
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in various...
Most decongestants are readily available over-the-counter in various...
01:03Olfactory Receptors: Location and Structure
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
01:29Anatomy of Respiratory System I: Upper Respiratory Tract
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract.