Related Experiment Video

Updated: May 12, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
09:40

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function

Published on: April 17, 2020

Early developmental outcome following surgery for oesophageal atresia

Karen Walker1, Robert Halliday, Nadia Badawi

  • 1Grace Centre for Newborn Care, The Children's Hospital at Westmead, Westmead, New South Wales, Australia. karen.walker@health.nsw.gov.au

Journal of Paediatrics and Child Health
|April 23, 2013
PubMed

Insights

Infants undergoing surgery for oesophageal atresia with or without trachea-oesophageal fistula (OA/TOF) showed lower expressive language scores at one year. This highlights potential developmental impacts of OA/TOF requiring further investigation.

Area of Science:

  • Pediatric Surgery
  • Developmental Pediatrics
  • Neonatal Outcomes

Background:

  • Oesophageal atresia with or without trachea-oesophageal fistula (OA/TOF) is a congenital condition requiring early surgical intervention.
  • The long-term developmental sequelae of OA/TOF in infancy are not fully understood.

Purpose of the Study:

  • To compare the developmental outcomes of infants treated for OA/TOF with healthy controls.
  • To identify specific areas of developmental delay in infants with OA/TOF.

Main Methods:

  • Prospective enrollment of infants with OA/TOF and matched healthy controls between 2006-2008 in New South Wales.
  • Developmental assessment at one year corrected age using the Bayley Scales of Infant and Toddler Development (III).

Main Results:

  • Thirty-one infants with OA/TOF and 62 controls completed assessments.
  • Infants with OA/TOF had significantly lower scores on the expressive language subscale (P < 0.05) compared to controls.
  • Associated birth defects were present in 44% of OA/TOF infants.

Conclusions:

  • Infants treated for OA/TOF demonstrate a developmental deficit in expressive language skills.
  • These findings underscore the potential impact of OA/TOF on infant development.
  • Further longitudinal studies are warranted to assess the persistence and functional significance of these language delays.
Abstract

More Related Videos

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection05:57

ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection

Published on: February 10, 2017

Technical Considerations and Approach to Redo Foregut Surgery04:14

Technical Considerations and Approach to Redo Foregut Surgery

Published on: September 22, 2023

Related Concept Videos

Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...