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Updated: May 12, 2026

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
The Italian version of the Nociception Coma Scale
Davide Sattin1, Marco Pagani, Venusia Covelli
1Neurology, Public Health and Disability Unit, Department of Scientific Directorate, Neurological Institute Carlo Besta IRCCS Foundation, Milan, Italy. davide.sattin@istituto-besta.it
Assessing pain in non-communicative patients is challenging. The Nociception Coma Scale (NCCS) has been translated into Italian, providing a valuable tool for pain management in Italian clinical settings.
Area of Science:
- Rehabilitation Medicine
- Neurology
- Pain Management
Background:
- Pain assessment is critical for chronic patient care and rehabilitation.
- Evaluating pain in non-communicative patients (e.g., vegetative or minimally conscious states) presents significant challenges.
- Standardized tools are needed to assess pain responses in these complex patient populations.
Purpose of the Study:
- To translate the Nociception Coma Scale (NCCS) from English to Italian.
- To ensure the accuracy and reliability of the Italian version of the NCCS for clinical use.
Main Methods:
- The translation process involved multiple translators and expert raters.
- A rigorous translation and back-translation methodology was employed.
- Quality ratings for each item were assessed on a scale of 0-100.
Main Results:
- All items in the translated NCCS achieved high quality ratings, with no item scoring below 90.
- The Italian version of the NCCS was successfully developed and validated.
- The scale demonstrated high reliability and accuracy.
Conclusions:
- The Italian version of the Nociception Coma Scale is now available for use by Italian clinicians and researchers.
- This validated scale will facilitate accurate pain assessment and management planning for chronic patients in Italy.
- The availability of the Italian NCCS is expected to improve care in rehabilitative and long-term care settings.
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