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Elimination of roquefortine in the rat
1Biochemistry Department, Imperial College, SW7 2AZ, London, UK.
Mycotoxin Research
|April 23, 2013
Abstract:
(14)C-roquefortine, given to ratsper os or intraperitoneally, was eliminated principally by the biliary route. Most of the given radiolabel accounted for had been voided within one day of administration. Roquefortine was not metabolised in rat liver homogenate but significant transformation to more polar products was evident in faeces.
